The Review on Azithromycin

Azithromycin is broad spectrum macrolide antibiotic with long half life and excellent tissue penetration. an azalide antimicrobial agent active in vitro major pathogens responsible for infectious of the respiratory tract, skin soft children. In children azithromycin usually given as either a 3- day course 10 mg/kg/day on first day,followed by 5 further 4 days. subclass microlide antibiotics. It derived from erythromycin methyl–substituted nitrogen atom incorporated lactone ring, thus making lacctone ring 15-membered. Pathogen that are generally susceptible to include Haemophilus influenzae (including ampicillin-resistant strains), Moraxella catarrhalis, Chalmydia pneumoniae, Chlamydia trachomatis, Mycoplasma pneumoniae Streptococcus pyogens streptococcus agalactiae. administerd once daily achieves clinically relevent concentration at sites infection, slowly eliminated body has few drug interaction.A five treatment administration (500 mg 1 followed 250 days 2-5 ) or three regimen days).